Our study provides insights into understanding psychotropic drug effects at the
single-cell level in the brain. The stimulant methylphenidate (MPH) and the
non-stimulant atomoxetine (ATX) are frequently used for the treatment of
attention-deficit/hyperactivity disorder (ADHD). However, the function of these drugs in
different types of brain cells and their effect on related genes remain largely unknown.
We highlight a novel approach to rapidly and cost-effectively explore the drug basis of
psychiatric disorders using Drosophila models, which provides a comprehensive resource
for gene function in the Drosophila brain and future drug research in psychiatric
Here, we built the website for visualization, which enable users to view single-cell
RNA-seq data, query specific gene expression in various cell types and search drug
We built ADHDdrug
that enable users to view scRNA-seq data and query
specific gene expression in various cell types.
Two drugs of the scRNA-seq data have been added in the datasets.
The latest version was released on Nov 17th, 2023.
The first version was released on Jan 12th, 2023.
We have developed EasyFlyTracker.It is an easy-to-use Python 3-based
package that can track and analyze Drosophila sleep and locomotor activity
based on video shooting.
The latest version package and website were updated on April 20th, 2023.
The first version package was released on Aug 1st, 2021.
The icon of the fruit fly on the top left is of our own design.
The picture on the right of the home page: Some elements were generated
according to our keywords through the AI drawing function of Wenxin Yige
online website (https://yige.baidu.com/) , and were modified on this basis. If
you want to use them, please cite us appropriately.